Life can take turns we are not willing to take. It can be dark, lonely, or just plain depressing. During these times a flare can present itself as depression and it's hard to cope.
What do I try to do? I get lost in the 80's... music that is. That music springs me back to a time that was whole for me.
What should you do? Find that hole that fills you. It could be your adolescence, your adult life, or your childhood. It could also be something completely different. Just fill your hole and life will be bearable.